The Yellow River Delta is rich in natural resources and has a unique ecosystem. The ecological protection and high-quality development in the Yellow River Delta have become a national strategy. Under the severe constraints of resources and environments as well as the serious degradation of ecosystems, the ecological protection and high-quality development of the Yellow River Delta urgently need the guidance and support of scientific and technological innovation. The implementation of coastal ecological farm and ranch is considered to be one of the important ways to achieve high-quality development. In order to create new models of green, low-carbon and circular coastal ecological farm and ranch in the Yellow River Delta, this paper analyzed the existing problems in coastal ecological farm and ranch, and put forward the high-quality developmental concepts and targets. At present, the unoptimized macroscopical planning, the incomplete industrial system, the imperfect innovation system, and the unstrengthened policy support of coastal ecological farm and ranch have restricted the high-quality development of coastal ecological farm and ranch in the Yellow River Delta. Furthermore, multi-driven high quality development approaches were raised as follows. Firstly, optimizing the macroscopical planning driven by water-salt scenario, that is, identify the complexity of the water-salt scenario and plan the layout reasonably; analyze the dynamics of the water-salt scenario and accomplish digital management. Secondly, highlighting the "chip" function driven by seed industry, that is, improve biodiversity based on native species protection; strengthen the cultivation of improved seed to enhance the driving force of industry; promote seed breeding to improve the coverage of seed industry. Thirdly, promoting model innovation driven by farm-aquaculture interaction, that is, connect land and sea to optimize industrial spatial layout; integrate farm and ranch, and establish linkage between Three Industries. Fourthly, realizing the intelligent upgrading of industry driven by equipment development, that is, build unmanned farms in saline and alkaline land; realize less populated farms and ranches on the tidal-flat area; create shallow sea intelligent ranches. Fifthly, innovating the collaborative paradigm driven by research-industry linkage, that is, integrate innovative elements to solve the problem of disconnection between industry and scientific research; financing through multiple channels to enhance innovation vitality. Finally, achieving industrial upgrading driven by governance policy, that is, integrate research and development resources and improve innovation ability; implement integrated development and strengthen the whole industrial chain; forward-looking layout of special research projects and innovative development modes. Therefore, stakeholders could construct new developmental models of coastal ecological farm and ranch in the Yellow River Delta with match of water-salt scenarios, integration of farm and ranch, and linkage of Three Industries, to realize the coordinated development of mechanization, intelligence, digitization and systematization. Our study is helpful to provide a reference for the high-quality development of coastal ecological farm and ranch in the Yellow River Delta.