工业生物技术的任务是把生命科学发现转化为工业产品、系统和服务，能够为经济发展创造新的机遇，受到世界各国的重视。发酵工程是工业生物技术的最重要组成部分，并且正在重塑发酵工业和轻工业。本文系统总结了发酵工程在大宗发酵产品转型升级、传统产业节能减排、食品加工过程安全问题解决和功能营养品生物制造四个方面的创新任务。最后，本文展望了发酵工程的发展趋势，发酵智能化技术与装备体系和发酵智能化工业新模式将引领发酵工程领域的未来。

Industrial biotechnology aims at transforming discoveries of life science into products, processes, systems, and services, which creates new opportunities for economic developments and is regarded as an important research field worldwide. Fermentation engineering is a key field of industrial biotechnology, which is rebuilding fermentation and light industry. In this paper, we systematically summarized four innovation tasks of fermentation engineering, including transformation and upgrading of bulk fermented products, energy conservation and emission reduction of traditional industries, solving safety issues of food processing, and biomanufacturing of functional nutraceuticals. Finally, development trends in fermentation engineering were discussed. The future development of fermentation engineering will be facilitated by technology and equipment systems for fermentation intelligentization and new industrial mode based on fermentation intelligentization.

国家重点研发计划（2017YFC1600403）