Abstract:A 22-day feeding trial was conducted to assess the compensatory growth response to different cyclic starvation and refeeding regimes in juvenile Liza haematocheila. The test was performed in the conditions of the water temperature:(19±2)℃, pH:7.2, salinity:3.5, the oxygen content was 6%,the same age(36 days), the similar size, the L. haematocheila juvenile were fed:twice a day,once a day,once 2 days,once 4 days,once 8 days(namely S0, S1, S2, S4, S8), cyclic feeding 20 d, sampling at 22 d. We measured morphological characters about the body weight, body length, body height, head length, length before anal and so on. The experiments were carried out using anatomy, Bonn's solution fixation, paraffin sections, H.E staining, optical microscopy techniques to observe the juvenile barracuda's structure, morphology of the digestive organs in different groups. The esophagus, stomach and intestines cortex height, tall columnar cells, wall thickness, muscle layer thickness and the size of the esophagus and intestinal goblet cells were measured. Using SPSS19.0 software for measurement data,we analysed the impact of intermittent starvation on their histology. The results showed:in terms of juvenile behavior, the cluster of S0 and S1 was strong, swift movement, the cluster of S4 and S8 was weak, when they were frightened, they were in sporadic distribution, and the movement was somewhat less. In terms of morphology, the individuals of S0 had the largest increase, almost with the same period the growth of juvenile fish in the nursery pond, individuals of S1 were smaller than S0, there was a significant difference between the groups in the weight in both S0 and S1; S4, S8 had varying degrees of damage,with a big head and a little body,stomach volume was reduced, wall thinning; intestinal wall thinning transparent, mesenteric fat disappeared because of atrophy. Liver volume was significantly reduced with the color change from the original pink to crimson yellow.In tissue structure, S0 inter-group's tissue has somewhat changed, but it was not obvious. S1, S2 had a significant increase in the mucus cells; the gastric cells developed, but the secretory granules decreased,intestinal folds height decreased significantly and epithelial cell height reduced, the striated border height in S0 and S1 did not change significantly;from S1 to S4,the striated border height gradually became smaller, even irregular, S4, S8 group striated border height reduced significantly. In addition, obvious changes could be found in gastrointestinal mucosa of S8 group with fewer endocrine granule,intestinal brush border broken off, height of columnar cells reduced significantly from the front to the rear of intestine,goblet cells was significantly smaller in volume, liver cell shrinkage, reducing the number of lipid vacuoles, cell boundaries obvious and irregular, pancreatic acinar narrow, irregular arrangement. The results showed that when juvenile L. haematocheila at intermittent short-term starvation,the fish could adjust itself accordingly in tissue structure, the compensation effect existed, but when the intermittent hunger had a certain period of time,and then the digestive structure will display some irreversible phenomenon.