The content of moisture,crude protein,crude fat,ash,glycosaminoglycans,saponin,the composition of fatty acids and amino acids and 16 kinds of elements were comparatively analyzed in body wall and internal organs of sea cucumber Apostichopus japonicus collected at Rushan.The results showed that the contents of moisture,crude protein,crude fat,ash,glycosaminoglycans and saponin averaged 90.67%,76.11%;49.75%,34.90%;6.56%,5.15%;27.50%,36.85%;7.47%,1.08%;0.062 2%,0.017 4%;respectively.21 kinds of fatty acids were found in both body wall and internal organs.Internal organs have more PUFAs,the EPA and DHA were the predominate fatty acids,accounting for 13.09% and 6.88%.Thirteen kinds of amino acids were detected in both body wall and internal organs,including 8 kinds of essential amino acids which accounted for 39.36%,39.93% of total amino acids.The two parts were both rich in flavor amino acids［19.07,11.57 g/(100 g)］such as glutamic acid(Glu),aspartic acid(Asp)and efficacy amino acids［10.78,7.06 g/(100 g)］such as argine acid(Arg).The AAS and CS of the essential amino acids of the internal organs were lower than those of body wall.Both parts are rich in minerals,especially elements Mg,Fe,Zn,V,Se.The contents of V and Mn in the internal organs are particularly rich.The internal organs of sea cucumber A.japonicus are the potential material for diet and medicine,which should be fully utilized.