An experiment was conducted to study the turtle plasmasol on turmor immunization , by feeding the turtle plasmasol to observe the inhibiting turmor trial and using MTT to assay the cytotoxicity of macrophages .The activities of SOD were observed to determine the effect of antiagting .The results showed that wild turtle and biomimetic turtle had shown marked inhibiting effect on S180 tumor growth (P <0 .01). The inhibiting tumor rates were 70 .69 % and 63 .17 % respectively .Significant increase(P <0 .01)was observed at the longevity rate on them, 40 .59 % and 39 .95 % respectively .The intruction of nitric oxide in murtur macrophages and macrophage-mediated cytotoxicity in wild turtle group and biomimetic turtle group were significantly higher than those of control group (P <0 .05 -0 .01).These observations suggest that turtle plasasol could be susceptible macrophage to increase NO production and improve the efficiency of killing tumor cells .Significant increase(P <0 .01 -0 .05)was also observed at the SOD activities between treatments and control , which indicated that turtle plasmasol could increase humoral immunity .